Lysine (abbreviated as Lys or K) is an α-amino acid with the chemical formula HO2CCH(NH2)(CH2)4NH2. This amino acid is an essential amino acid, which means that humans cannot synthesize it. Its codons are AAA and AAG. Lysine is a base, as are arginine and histidine. The ε-amino group acts as a site for hydrogen binding and a general base in catalysis. Common posttranslational modifications include methylation of the ε-amino group, giving methyl-, dimethyl-, and trimethyllysine. The latter occurs in calmodulin. Other posttranslational modifications include acetylation. Collagen contains hydroxylysine which is derived from lysine by lysyl hydroxylase. O-Glycosylation of lysine residues in the endoplasmic reticulum or Golgi apparatus is used to mark certain proteins for secretion from the cell.
Synonyms
Lysine
L-Lysine
L-2,6-Diaminocaproic acid
(S)-2,6-diaminohexanoic acid
Lysine acid
LYS
Lysina
(S)-α,ε-diaminocaproic acid
L-Lysin
Lysine acetate
Lysine dihydrate
Lysine monohydrate
Lysine hydrochloride
(S)-lysine
L-lys
6-ammonio-L-norleucine
Lysinum
Brand Names
Aminosyn II 10% With Electrolytes
Perikabiven
Aminosyn 5%
Aminosyn II 8.5% M In 20% Dextrose (dual Chamber)
Clinimix E
Essepna
Kabiven
Aminosyn II with Electrolytes
Novamine
Aminosyn II with Electrolytes in Dextrose with Calcium
Olimel 7.6%
Aminosyn 10% W Electrolytes
8.5% Freamine III
Olimel 5.7% E
Smofkabiven Peripheral
Primene 10%-liq IV
RenAmin
2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose
Primene 10%
Aminosyn-PF 10%
Aminosyn-PF
4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose Quickmix
2.5%travasol Amino Acid InJ.W.eleC.W.25%dex
Nephramine Liq IV
4.25% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose
4.25% Travasol Amino Acid Injection Without Electrlytes In 10% Dextrose
Olimel 4.4% E
Travasol E
Aminosyn II in Dextrose
FreAmine III
Clinisol
Aminosyn II 7% With 50% Dextrose
2.75%travasol Amino Acid InJ.W.eleC.W.5%dex.
Renamin (amino Acids) Injection
Aminosyn RF Injection
Vamin N
4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose
4.25%travasol Amino Acid InJ.W.elecw.5%dex.
Nutrineal Pd4
20% Prosol
Aminosyn 8.5% Injection With Electrolytes
Plenamine
Aminosyn II 8.5% Injection
Travasol Amino Acid Inj 5.5%
4.25% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose
Olimel 5.7%
Aminosyn II and Dextrose
Aminosyn Sulfite Free
Vamin 18 Electrolyte-free
Travasol Amino Acid Inj 8.5%
Olimel 7.6% E
Smofkabiven Electrolyte Free
Aminosyn 3.5% M
Aminosyn II 7% Injection
Smofkabiven Extra Nitrogen
5% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose
HepatAmine
Aminosyn 7%
Primene
4.25% Travasol Amino Acid Without Electrolytes In 5% Dextrose Quickmix
Clinimix 2.5% Travasol Aa Without Electrolytes In 10% Dextrose Injec
Aminosyn
Travasol Inj Without Electrolytes 8.5%
Aminosyn-PF 7%
ProcalAmine
Aminosyn II 7% M In 10% Dextrose(dual Chamber)
Travasol Inj Without Electrolytes 5.5%
Olimel 3.3% E
Travasol
Quick Mix 2.5% Travasol Aa With Electrolytes With 25% Dextrose Injec
2.5% Travasol Amino Acid Injection Without Electrolytes In 10% Dextrose Quickmix
Aminosyn II In Dextrose Injection
Aminosyn RF
4.25% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose
Premasol - sulfite-free (Amino Acid)
2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose Clinimix
TrophAmine
2.75% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose Quickmix
Aminosyn II 7% With 10% Dextrose
NephrAmine
4.25% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix
Smofkabiven Extra Nitrogen Electrolyte Free
Effervescent Potassium Chloride
Xyzmune
4.25%trav. Amino Acid InJ.W.O.elect.5%dext.
Aminosyn II 5% Inj
Synthamin
Periolimel 2.5% E
4.25% Amino Acid Injection Without Electrolytes In 20% Dextrose Quickmix
Aminosyn II
5% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose
4.25% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose
Clinimix
2.75% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix
FreAmine HBC
ProSol
2.75% Travas. Amino Acid InJ.W.elecw.25%dex
Lysakare
Imubolic
Olimel 4.4%
Hepatasol
Aminosyn 8.5%
Aminosyn HF
Smofkabiven
5% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose
Aminosyn II 8.5% With 50% Dextrose
Indication
Supplemental lysine has putative anti-herpes simplex virus activity. There is preliminary research suggesting that it may have some anti-osteoporotic activity.
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
