VIB

3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM

Created:	2001-04-17
Last modified:	2020-01-26

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22 entries where VIB is found as a standalone ligand

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Chemical Details
Formal Charge	1
Atom Count	35
Chiral Atom Count	0
Bond Count	36
Aromatic Bond Count	11

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Chemical Component Summary
Name	3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM
Synonyms	THIAMIN; VITAMIN B1
Systematic Name (OpenEye OEToolkits)	2-[3-[(4-amino-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
Formula	C₁₂ H₁₇ N₄ O S
Molecular Weight	265.355
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	n1c(c(cnc1C)C[n+]2c(c(sc2)CCO)C)N
SMILES	CACTVS	3.341	Cc1ncc(C[n+]2csc(CCO)c2C)c(N)n1
SMILES	OpenEye OEToolkits	1.5.0	Cc1c(sc[n+]1Cc2cnc(nc2N)C)CCO
Canonical SMILES	CACTVS	3.341	Cc1ncc(C[n+]2csc(CCO)c2C)c(N)n1
Canonical SMILES	OpenEye OEToolkits	1.5.0	Cc1c(sc[n+]1Cc2cnc(nc2N)C)CCO
InChI	InChI	1.03	InChI=1S/C12H17N4OS/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15)/q+1
InChIKey	InChI	1.03	JZRWCGZRTZMZEH-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

DrugBank ID	DB00152
Name	Thiamine
Groups	nutraceutical approved vet_approved investigational
Description	Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS. It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of Beriberi. Thiamine plays a key role in intracellular glucose metabolism and it is thought that thiamine inhibits the effect of glucose and insulin on arterial smooth muscle cell proliferation. Thiamine plays an important role in helping the body convert carbohydrates and fat into energy. It is essential for normal growth and development and helps to maintain proper functioning of the heart and the nervous and digestive systems. Thiamine cannot be stored in the body; however, once absorbed, the vitamin is concentrated in muscle tissue.
Synonyms	Antiberiberi factor Aneurin Thiamine mononitrate Thiamine Thiaminum Thiamine chloride thiamine(1+) ion Tiamina Vitamin B1 Thiamine hydrochloride Thiamin thiaminium thiamine(1+)
Brand Names	Toni Com Liq L.C. Supplement Opti-manganese + B1 + C Caplet Childrens Multiple Vit and Min Chew Tab Floriva Plus Corvita Duet DHA Balanced Stress Formula Vasculine Fortamines 10 Capsules Dexatrim Tablets Dialyvite 5000 Osteo-force Multi Vitamin with Fluoride RenaPlex Super Daily No 2 Tricare Prenatal DHA One With Folate Lorid Multivitamins and Multiminerals Formula Regular Tablet Mycelized Childrens Multi-vitamin Liq Dialyvite 3000 Vitamin B-1 Thiamine HCl 100mg H.W. Children's Chewable Multi Vit & Mineral Chew.multiple Vits.with Extra C for Children Amladex Acti-MN + B1 + C Caplet Multi-vitamines Enfants Comprime Vitamin B-1 100 Mg Tablets Edge OB Super Vita Vim Multivitamins and Minerals Multi Vite Liq Adult vitaMedMD One Rx Derma-force Vinacal Vita Vim Multivitamins and Minerals Tab D'pantothenic Acid-B1-B2 Tab Active FE Formula B Children's Chewable Multivitamins and Minerals Floravit - Syr Kimchi Vitamin chewable multivitamin Virt Nate Trinatal GT Multiple Vitamin Tab Revit Multi-vitamins and Minerals Vita-vim - Tab Formula Hh Davimet One Daily Vitamin and Mineral Dietary Supplement Provida DHA Vigo Multivitamins Drops/lozenge Prena1 Zintrexyl-C DuetDHA Complete Multi-vitamins With Minerals Children's Chewable Tab Fortamines-10 Comprimes One-A-day Advance Men's Obstetrix EC Thiamine HCl Inj 100mg/ml Nephron FA Children's Multivitamins Thrivite 19 Soluvit N Nephrocaps Balanced B50 Complex Methaver Tricare Prenatal DHA One TL-Folate Vol-Care Rx CitraNatal 90 DHA PNV-Select Stress Formula + Iron Phytofortis + Calcium A-D Strovite One Caplets THIAMINE HYDROCHLORIDE injection, solution Xyzbac Vitrexyl plus Iron TL-Fluorivite Strovite Forte Caplet Low Potency B Complex Tab NESTABS ABC Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA Vita-B Efferlife Multivitamins and Minerals Poly-VI-sol Drops Nutra Boost Beminal With C Fortis Cap Vita Vim With Beta Carotene-caplet Adult Formula 50+ B-complex With Vitamin C, Biotin, Folic Acid Corvite Vit B Complex Ctr Prenatvite Plus Balanced B-100 B-complex Vitamins Tab Multipack II Prenatvite Supravite Stress Avec Vit E Cuivre Et Zinc Swiss One Multivitamin and Mineral Caplet Children's Chewable Multiple Vit.plus Iron Multi-Vitamin Fluoride and Iron Drops NESTABS Prenatal Multi-vitamin/Mineral Supplement Fortaplex Inj Stressmates MVC-Fluoride Surbex-500 With Iron Kaydia Patch Myhephron Dialysis and Stress Supplement Gynedyn Tab Super Multi Twin G.F. Powder Vanilla Flavor Dynam Ampoule Et Tablet Keylosa Infa Drops Multivitamins Multiple Vitamins & Minerals Tablets Maxi 6 Liq Q.T. Vitamin and Mineral Drink Mix Vitazyme Sopalamine/3b Plus C One A Day Advance Fem Prenatol-M Folivane-OB Venexa FE Multiple Vitamins Childrens Chewable Vitasure Original Bioscal Forte Multi-vitamin Supplement Capsules Floriva Nutra-clear Multi Vitamin & Minerals Vitamin B + C Cap B Complex W C and B12 Inj AzesChew Magnum-75 Vitamin and Mineral Supplement Balanced B-50 B-complex Vitamins, Timed Rele Dialyvite Supreme D Chromease Tab PrePLUS Xvite Omega-3 Rx Complete Kids Stuff With Iron Tablets Iron 25mg With Vit B-cmplx, Vit C, Cu & Mo Advanced B & T Formula Multivitamin Complex-75 Reaphirm Plant Source DHA Xyzbac G TriAdvance Natavite Children's Chewable Multivitamin and Multimineral Vitamines Et Mineraux Davimet with Iron Diaplex Stress Formula Multivitamin Tablets USP Surbex-500 With Zinc Children's Chewable Multi Vitamins Multivitamins and Minerals - Complete Kid's Choice Children's Chewable Vitamins - Tab PreNatal Vitamins Plus Foltabs Prenatal Natal PNV Vitaflex Dietary Suplement Pnv-VP-U Vit B1 Ctr Srt 100mg Kindervites Numark Multivitamins tensioSAN Zatean-Pn SetonET Focalgin CA Multi Vitamin and Mineral vitamin Prenatal Bal-Care DHA Essential Paramettes Chewable Multivitamins Plus Iron Viva Kids - Tab Vitamin B Complex + C 300mg Cap Thiamine Folivane-Plus with Ascorbic Acid Precursors B-plex 100 Multivitamins W Iron Prenatal Vitamins Plus Pretrate Complexe B 75mg VitaXyme Neo-vites & Minerals Tab Complex 5 - Pwr Hylazinc Multi-force for Adults Tab PNV Prenatal Vitamin Plus Vitamin A B-complex Virt-Caps B Complex W Vitamin C Fortis Cap Pregnancy Multivitamin Vasula Tab N.E.U. Complex Bev 29 Tab For Kids Only Chewable Multivit. Plus Iron TriphroCaps DuetDHA Balanced Multi-force for Women Tab Nutrifer Plus Tablets Garfield Chewable Multivits Plus Iron Tab Synergistic Manganese Capsules B Complex With C 300mg Zalvit Formula Gm Lipotropic Ctr Poly-Vi-Sol Venexa Vitamin B Complex 100 Tab PreQue 10 Vyo Cylate - Pwr Classic Swiss One 10 Multivitamin and Mineral Tab Thiamine HCL 100 mg Centratex Se-Tan PLUS Complexe B-75 MYNEPHROCAPS DIALYSIS/STRESS Vitamin Supplement NataFort vitaMedMD Rx Plus Maltlevol 12 Liq Fortistress Tab Dialyvite with Zinc Mini-B Tab Multi Plex II - Tab Somavit Brand Vitamins and Minerals Complex Mega Plex IV - Pck Carbassist Tablets Essential Vitamins and Minerals Multi-Vit with Fluoride PM Caps B With C 500 Cap bioJET Prenate Elite Balanced B 125 Srt Supravite 10ml Ampoule Stress Complex 600 Avec Vit E Cuivre Zinc Vitamin B1 Tablets 100mg Virt-Tabs Vitamin B Cpd W Vit C Tab Alertonic Choice OB DHA Vitrexyl healthy mamaBE WELL ROUNDED BE WELL ROUNDED P.R.O. Complex Natal-V RX Multi-vitamin/Multi-mineral Duet DHA 400 Swiss One Timed Release Tab Multi-12 Pediatric Multivitamin with 0.25 mg Fluoride Ellis Tonic Vitamin B Complex W C 300mg Tab Vitramyn Megavites Tab Palm Springs Multvit and Min Tab Omnivex Childrens Chewable Tab Materna-tab SetonET-EC High Potency Multivitamins & Minerals Caplets Multi Vitamin Drops with Fluoride with Iron Hill.vite Chewable Multivitamins Plus Iron Earthpals Children's Chewables Multi-vitamin & Mineral Tablets Kanga-kid Vitamins & Iron Complete Multivitamins and Minerals for Children Multi Vitamins & Minerals Spectrum Performa Multivitamins and Minerals Tablets Quflora Pediatric Drops Children's Chewable Multiple Vitamins With Iron Tablets (chewable Tablets) Multivitamines Folica-V Livron Plus Tab Chewable Children's Complete Multivitamins With Essential Minerals Twin G.F. Powder Active OB Iron Polysaccharides Folic Acid DHA Glyco-aide Tab Vp-heme Ob Harvest Of Values All B Complex Tab Multi Vitamin-mineral Formula Thrivite Rx K.L. Vitamin-mineral Vitamin B Complex 50 Central-vite 18 Essential Poly-Vite/Iron Oral Solution Florafol FE Pediatric 0.25 mg/mL Multivitamin and Fluoride Liquid Drops Fibrik Vita Plex Tab Nutrol-B-complex Thiamine HCl Tab 100mg Zoo Chews Multivit-liq Multi Vitamin - Mineral B Plus C 300mg Timed Release Poly-Vi-Flor Multi-Vitamin with Fluoride B Compound 50mg Tab Quflora Pediatric Multi-Vit-Flor Childrens Chewable Vitamins RE Nata OB Sopalamine 3b Plus B-50 Complex Tab T.R.I. B-plex Src Vitamin B1 Moms Choice Rx Hemarexin Tab B-50 Complex Extra Once A Day Quflora FE Pediatric Drops Revit Plus Cap MultiVitamin with Fluoride Drops MultiVitamin, Iron and Fluoride Drops Thiamine Hydrochloride Escavite D Senior Multi One Stress Vitamin B With C Complex Tablets Supravite C 1000 Total Living Concepts Formula One - Tab WesCaps Multiple Vit Plus Iron Tab Se-Plete DHA Balanced B100 Jenliva Multiple Vitamins Tab Multiple Vitamins and Minerals Tandem OB Tricare Prenatal 2-part Daily Prenatal Vitamin System Prenatal Plus Childrens Chewable Vitamin Tab Renate Children's Chewable Multi-vitamin Kenwood Liquid Supplement Se-Natal One Stress B With 1000 Mg Vitamin C Lipovite Lysamine Diet Supp Amp-tab Se-Natal 19 Super Pantoplex Nrg Plus Liq CitraNatal Essence WesCap-C-DHA B-100 Complex Tablets Stress Tab With Iron and Vitamin E Stress Tablets Neo-bex Injectable Ply Vi Sol Chewable Tab Dermamed Nutrition for troubled skin Elite OB Prenatal Multivitamin Gestamine Comprimes Super Vita-vim With Beta-carotene - Tab Multinate DHA Supravite Pour Enfants Vitamine Du Groupe B Plus Fer - Liq Z Bec Tab Genicin Vita-Q Escavite B 6 Plus B-Combo Vp-heme Ob DHA One A Day Multiple Vit W Minerals Re Ob 90 DHA Cavan Folate DHA Multi Vitamin Plus Iron Multi-actin Super Kids Chewable Multivitamin Multimineral (chewable Tablets) One A Day Tab Liqui Vita Chewable Multiple Vitamins Plus Iron Tab Multivitamins PR Natal 430 ec Complete One A Day Tab TL-Care DHA Vita B Complex Tab Cavan Alpha Vitachrom Gc Revitex Ampoules Et Comprimes Distilpure Msm Stress B & C Caplet Hypo Vites Tab Swiss One Abavite Dayavite Poly-VI-flor Pro Hers Vanilla Liqui B Complex Flintstones Multiple Vitamins Doctor's Choice Brand for Men Hyporyl - Tab Virt-Nate DHA Somarexin and C 1000 Corvite Free Multivitamin & Minerals (iron Free) C-B Complex Vitabanks Vitamin Tab Mega 13 Multivitamin Formula INATAL Ultra Stress Tab Multivitamines Plus Fer Pour Enfants (chewable Tablets) Virt-Vite Plus Penta-thion Pwr Prometa OB Complete 400 Prenatal Vitamin and Mineral Supplement Tab RE Nata P.N. Vitamin-mineral Drink Livron Plus Ampoule Acti-thiamine Caplet 100mg Multitabs Davimet-M NephPlex Rx TriStart DHA Multi-Nate 30 OBTREX DHA Combo Pack Prenatal Vitamins Plus Low Iron Orifer F Thiamine Hydrochloride Injection USP, 100mg/ml Cavan Prenatal PreTAB Everyday Multiple Vitamins Multivitamins and Minerals for Men Thiamine HCl Tab 50mg Children's Chewable Multiple Vitamins - Tab Maxum Multi-vite Enrich Core Pack - Children Vitamin and Mineral Supplement Prenatal Mega Antioxidant Viamon Ampoules Et Comprimes Everyday Multiple Vitamins With Iron Maximum Once A Day FolaGent DHA Mega Vitaminerals Vitamin B1 Tab 100mg Duet DHA 400 ec B Plus C 300 mg Prena1 Plus Vita-B-75 Cap Vitamin B-Complex Vitamines Et Mineraux Enfants 970 Chewable Multiple Vit Plus Iron for Children Paramettes Chewable Multivits With Iron Tab Mega Plex III - Pck Prenara Vitamin B Compound W C Tab 500mg Multi-Vit with Fluoride and Iron Formula Pro-B Hi Potency Balanced B-100 Complex - Tab Multivitamin Drops with Fluoride One-A-day Advance Fem - Tablets Vol-Plus Women's Formula Vitamin B Compound With Vitamin C Fortis Capsule Dtc Vitaphil DHA 50 Plus Children's Chewable Multivitamin Complete With Minerals Women's Change Formula Stress B Complex With C,e, Zinc and Copper Beminal With C Fortis Pws Revit Tab Multiple Vitamins and Minerals Tab Vol-Nate Nephrocaps-QT B-complex Tab Complexe B Compose 75 B6 Plus Tab Childrens Chewable Multiple Vitamins Inatal Advance Prenatal Vitamin and Mineral Supplement Vitamines Et Mineraux Comprimes Folitin-Z Concept DHA Insur-all Vitamin Supplement Florafol Pediatric 0.25 mg/mL Multivitamin and Fluoride Liquid Drops Mega Balance Vitamin B Complex Plus C 300mg Timed Release Virt-PN Multivitamines Et Mineraux Reguliers / Regular Multivitamins and Minerals B-complex Tablets Multivitamins and Minerals With Betacarotene Tablets Vege Swiss One Multivitamin W Chel Mins Tab CompleteNate Chewable Am Caps Multi-kid Kids Stuff Tablets Formula Lf Croq-vit Pour Enfants Multivitamine Neonatal Plus Vitamin Dalivit Multi Vitamin and Fluoride Lipo-B-C Tab Renate DHA Rocky Mountain Multiple Vit and Min Mega Tab Super Stress Mega B Plus 1000mg Vit C Tab Mangadyn Pregvit Folic 5 Complete Natal DHA Multi Enfants Tab Niva-Plus Vitamines Pour Bebes Et Enfants Swical-energy-2 Neonatal Vitamin Prenatal Formula Tab Tricare Prenatal Quick Dissolve Multi Vitamin, Iron and Fluoride Antlerviron Iron Folate Plus Vitafol Ultra Multra With Iron Multi-Vitamin Fluoride One Tablet Daily Mens Formula ahoSAN Vp-pnv-dha Quflora FE Beminal Fortis Elx Vc II L.G.I.T. Supravite Stress Avec Vit E Et Fer Liqui B Complex Plus Kanga-B Vitamin B Group + C Orti B Childrens Chewable Multivitamins W Iron Vitamin B Complex + C 600mg Tab Virt-Advance Materna - Tab B Totum 500 Stresstabs + Zinc-copper Meplex T 750 Zavitrol Men's 50+ B 50 Capsules Multi-vitamin Dietary Supplement Multicaps Complete Mega B PreNatal 19 Appedrine Enviroflex - Tab Preplus Ribotin-E Triveen-Duo DHA Balanced B-50 Complex Synergistic Manganese Cap Balanced B-complex Vit + Vit C&e Tab Tricare Prenatal DHA One Rx Multivitamin Dexatran RE FAC-x Spark Cap Timed Release B-complex 100 Vitamine B1 Tab 100mg USP Dia-vite Novel Vita Prenatal and Post Partum Supplement WestGel DHA Body Rox Zoo Chews Plus Iron Multiple Vitamin Plus Minerals Tab Children's Chewable Multi-vitamin Complete With Minerals Vitafol Plus Multiple Vitamins W Iron Tab Multiple Vitamins With Iron Tablets Multivitamin & Multimineral Neo Bex Elixir B Stress C + Iron & Vite Vita Balance 2000 Fusion Plus Virt-C DHA Children's Multivitamins With Iron Prevital Tab Vitaday Junior Tab Multiple Vitamins With Iron Twin Ultra Liquid Fruit Punch Flavor Stress B Complex With C, E & Iron Vitafol Fe Plus RayaVit Replavite Pnv-OB-dha Vitamin B1 Tab 2mg USP Chela-chromium 200 Maltlevol Liq Taron-C DHA Omniquin Daily Energy Brand B-complex Multi Vitamin Drops with Fluoride and Iron Flintstones W Extra C Tab Chewable Adult Multivitamins With Minerals Multiple Vitamins Plus Iron - Tab OB Complete DHA Permathene-12 - Caplet Vena-Bal DHA 24 Multivitamins + Minerals Forty Plus Vitamin Supplement Multi-Vitamin Flinstones Multiple Plus Iron Thiamine HCl 100mg W C 20mg Flintstones Multiple Vitamins Plus Iron Multiple Vitamins W Minerals Tab Men's Multi Master Formula Formula D.S. Lexazin Vitaday Tab Complete One-A-day - Tab Megavite Rx Vitaphil 90 DHA Geritol Liquid B Complex W Vit C W Non-med Yeast&liver Tab Se-Natal 19 Chewable Formula F L W Vitranol Vinate AZ Multi Flow Tablets Gemvites Jr Tab Chewable Vitamin B Complex Allbee With Vitamin C Cap Adult Infuvite Multiple Vitamins Infantol Drops B Complex 500 Tab Liquid B Complex 50 NovaFerrum Multivitamin with Iron Pediatric Drops Vitafer - Liq Super-pote Vitamin Supplement B Complex 25mg Vitamin Supplement Children's Chewable Multi Vit W Iron Hemocyte Plus Nutrilite Double X Usana Megavitamin Tablets - Tab Materna Chela Iron Plus C,b Complex Mega Capsules Tricare Prenatal Vita-Pac Stress B Capsules With Vitamin C Innersource Tab MI-Vite RX Bugs Bunny Chew Multi Vit Plus Iron Concept OB Multivitamins and Minerals for Young Men Natural Source Spectrum With Beta Carotene PureFe OB Plus Poly-Vi-Flor with Iron Tini-cal Ampoules C. Vit-min Formula Gtf-vitamin-minerals & Pancreatin Tab Junior Multi Vitamins - Regular MultiVitamin Drops with Fluoride and Iron Nutri-Tab OB One Per Day Vitamin and Mineral Dietary Supplement PNV Ferrous Fumarate Docusate Folic Acid Provida OB B Vitamin Compound With B12 Thunas B Complex Plus C 300mg Tab One Daily VITES Thiamine Hydrochloride Injection, USP Vimeral Tab Alkadrenergy Tablets Select-OB Plus DHA Prenatal Supplement Plus DHA Mebolic Integra Plus Prenatal Vitamin and Mineral Supplement -tab Multi Pro MultiVitamin with Fluoride Chewable Glyco Plus Ect Multi Rol Vitamine 110 Liq Isotonix Multitech Vitamin Mineral Supplemen Multi-12/k1 Pediatric Multivitamines Pour Enfants (chewable Tablets) M-Natal Plus Vitamin B Compound W Vit C 250mg Tab B Complex 50+ Caplet Timed Release B-complex 50 HemeNatal OB Zyvit Infuvite Pediatric Wellness Formula Multi II IV Vi Tab Multi Spectrum - Tablet Essential B Tablets Children's Vitamins W Iron Chewable Folika-NC P.N.P. Vitamin Drink Virt-Nate Multi-Vitamin Fluoride Drops B-100 Vitamin Supplement Folet DHA Multi-11 Nata Komplete Prenatvite Complete Phosthenine Vitamines Et Fer (ampoules Buvable) Adeks - Dps hormaSAN forte Vol-Tab Rx Hi Potency B Complex W Chelated Minerals Focalgin 90 DHA MultiVitamin with Fluoride Vitalife - Capsule Pre-Tabs DHA Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA Vitamin B Compound Tab O-Cal Prenatal Vitamin Genicin Vita-S Sun-rype Vitaburst B-plus - Tab Multi B Multi Nt-OX NataChew PR Natal 400 ec Multivitamins and Minerals for Women Multra Plex Stress Forte Plus Lipotropic Factors Multi Vitamines - Liq B Complex 50 Vitamin Cap Multiple Vitamins Multivitamines Et Mineraux Junior Regulier C.R.T. X Multivitamin & Mineral Powder Mix Multivit Et Fer Ampoules Et Comprimes Paramettes Adults Vitamin B1 100mg Prenatabs FA Vitamin and Mineral Supplement - Liq Cyroplex Prefera OB plus DHA Multi Plex I - Tab Prim - Royal P.M.T. Timed Release B Complex 100 Srt Ultra Enerforce Foliflex Multivitamins for Children Garfield Chewable Multivitamins Tab Vita Day Tab Grand Master Formula Tab Chewable Multivitamins Pnv Ob DHA Folica BE Livita Children Children's Chewable Multivitamins With Minerals Vital Be-100 Childrens Chewable Multiple Vitamins Tab Multi-phyto Capsules Multiple Vitamins Plus Iron Tab Potassium Plus Vit B Complex Children Choice Multivitamin W Iron Chew Tab B50 B Complex Tab Stress Formula Multi-B Comp + 500mg Vit C Cap Zeldana Pro His Mint Prenatal Vitamins and Minerals Tablets Relnate DHA PureVit DualFe Plus M.V.I. Adult Multivitamins and Minerals for Young Women TM-Vite RX Spectrum 2 Cap Hi Potency Stress B Tension With C Master Key Multi Vitamin Multi Mineral Formula 2 Men's Biomultiple Vitamin and Mineral Supplement Natalvirt 90dha Q.T. #4 Vitamin and Mineral Dietary Supplement Vitrexate Multi #2 Tonimol Cap Liq Stress Tab With Zinc, Copper and Vitamin E Vit B Complex Plus Vit C 550mg Vitafol Caplet Time Release B 100 Compound - Tablet Livita Adults Extra P.N. Vitamin-mineral Drink Mix Kanga Sport Vitamins B & C Plus Minerals Children's Chewable Multi Vitamins With Iron Tablets B Complex Tablets Vigem 12 Liquid Alsimine W Vitamins A D Allbee With C 550 Cap Flintstones Multiple Vitamins Tab Deriton Pregnancy Multivitamin Folic 5 Vitogen B Stress C Vit E Zinc & Cop Children's Chewable Vit and Min Tab B-1 Caps 500mg Vit-HA Multi Vitamin and Zinc Supplement Hi Potency Multi Tab Medi Msm (methyl Sulfonyl Methane) PNV Prenatal Plus Multivitamin Fem Time Tab Obstetrix DHA Combo Pack Paramettes Syrup Allbee C 800 Tab Mvc PROTECT IRON Liquid Phytovim Cap Puralor Bev B-150 Stress B-complex Plus Iron With Vitamins C&e Childrens Chewable Multivitamins Vita-worth B-complex Tablets Iron, Vit & Min Supp CitraNatal DHA Supplement De Multivitamines Infusion Arome Fruits Rouges Stress Formula Tab Swical-energy 3e Age Vitamin B1 100mg Tablet Vitogen B Stress C600 PR Natal 430 Duet DHA Formula O.C. M.V.I.-12 Tender Age Multi Vitamins Neomultivite Protect Plus SO 60 Phytopure Pediatric Infuvite Multiple Vitamins Women's Biomultiple Vitamin and Mineral Supplement Reno Caps Tandem Plus Vitamin B1 Tab 100mg USP Cavan-EC SOD DHA Folic-K Cavan Folate OB Maxi 10 Tab Multiple Vitamins - Tablet Multiple Vitamins With Minerals Tablets Polymine Avec Zinc Et Cuivre Neonatal19 Pregvit Folic 4 RenaPlex-D One A Day Advance Adults 50+ Multivit with Fluoride Stress Formula Vit B With C Complex Swiss One Multi Vit & Chel Min Tab Thiamine Hydrochloride Inj 100mg/ml USP OB Complete Petite Right Choice A.M. Multi Formula - Caplet Stress Formula B-comp + 500mg Vit C Tab Stress B Complex With C, E and Iron Tab Children's Chewable Multiple Vitamins With Extra Vitamin C (chewable Tablets) Phytoplex B Liq Revitalize Multi-vitamin and Mineral Complex Bewon Elixir 0.05mg/ml Virt-Pn Twin Opti Pwr Vitamin B Complex W C Tab Twin Ultra Liquid Orange Flavor Vitafol-OB Plus DHA Prenatal Supplement Plus DHA Daily Balance Tab Nutri-Tab OB plus DHA Totalvit Plus B Complex W C Forte Cap Vtb Vitamin and Mineral Supplement Envirocomplex Kanga-kid Multi-vitamin & Mineral Vitamin B1 100 mg Paramettes Multivits Plus Iron Tab (teens) For-2 Ventrixyl Children's Vitamins Chewable THIAMINE HCl Chewable Multiple Vitamins Plus Extra C Childrens Chew Multi Vitamin Tab For Kids Only Chewable Multivitamins - Tab Vitaplex Premium Prenatal - Tablets Thiamine HCl Tab 25mg Multi - N.T.O.x Formula - Tab B-complex 50 Multisol M.V.I. 12 Maxine Vitamin and Mineral Supplement B50 Complex PreferaOB Trinatal Ultra M.V.I. Paediatric Multinate DHA Extra Mor-vites Tab Prenatal Plus Multivitamin Plus DHA MiniCaps Finazol Prenatal Supplement - Tab Supravite Stress Avec Vit E HemeNatal OB plus DHA NEONATAL Complete Ultimate Tab Nutra-Z Card-floe II Tab Chewable Multiple Vitamins for Children Dothelle DHA O-Cal FA multivitamin Virt-Bal DHA Plus Cda-21 Vitamins With Non-medicinal Probiotic Complex Multi 1000 Twin Ultra Liquid Lemon-lime Flavor Vyqua Virt Vite GT B C Antistress Cap Century Complete Multi-vitamins Animal Shapes w/Iron Chewtabs Avon Vitadvance Multi-kids Complete Prenatrix Azesco Vitamin B Tablets PNV-First Gtf Support Caplet Hylavite Multi 12 Injection Stress B Complex With C and E Tab WesNate DHA Revival 1 Tab Hemarexin Liquid and Drinkable Ampoules Complete-RF Prenatal Supravite Bouteille 250ml Oncovite Vital-D Rx Complete Multivitamins and Minerals Tablets Timed Release Balanced B-50 B-complex Vitamins Tab Cal M Tab Folika-T Vitamin B Complex Tab Biovim Tab WesNatal DHA Complete Multivitamin with Fluoride V-Natal Formula Gly Super Stress Capsules One A Day Advance Adults Multi Vitamin Drops with Fluoride PNV Tabs 29-1 VP-Vite Rx Children's Chewable With Iron TRONVite Gesticare DHA Chela Potassium Plus Hi Potency B52 B Complex Tab Leritone Junior RE Prenatal Multivitamin with Iron Multivitamin with fluoride Multitol-M Multiple Vitamins and Minerals Capsules Neo Vites Tab C-Nate DHA Se-Natal Multivitamins and Minerals Tablets Surbex 500 Filmtab Multi Tabs B-complex-50 Tab Bacmin B-plex Dialyvite Multivitamins W Minerals Extra Strength Childrens Chewable Multiple Vitamins Plus Fe B-complex 100 Thiamine Hydrochloride Inj 100mg/ml Floradix Formula Liq New Chapter's D'adamo 4 Your Type Multiple for Type O Ultimate OB DHA VIL-Rx Biovita Multivitamin with 1.0 mg Fluoride Vitamin B Complex Suppl Viva CT Prenatal Prenatryl L-Methyl PNV DHA FloraFol Vita-vim With Beta-carotene - Tab Bugs Bunny and Friends Multiple Vitamins Multivitamines Et Mineraux Prenatal, DHA WesTab Plus Fizz Multivitamins for Kids W C Loz Multi-Vitamin Drops with Fluoride and Iron Chewable Multiple Vitamins Tab Orange Flavored Crystal Chews Tab Super B Compound W 500mg Vit C Vitamine B1 100 Mg - Tablet Super Charged Energy Vita-Rx Diabetic Vitamin Betaxin Liq 100mg/ml Select OB Children Choice Multivit Chewable Tab Twin Ultra Liquid Grape Flavor C-force Balanced B-100 Timed Release Infuvite Adult Stress B&c Tab Renal Caps Dialysis/Stress Vitamin Supplement FolaMed DHA B Complex With C 300mg Tab Swiss Total One Adeks Tablets Trinatal Rx 1 V & M Vitamin and Mineral Supplement Feminique W Iron and Calcium Tab G.A.S. Complex For Kids Only Chewable Multivitamins Glyco Lite Ect High Potency Vitamin B Complex + C Tab PreGen DHA Beminal W C Fortis Inj Paire OB Plus DHA Nitro Vites - Tab Premium Prenatal B-50 Hi Potency B Vitamins Tab Dexivite 50 Plus Multiple Vitamins & Minerals Bal-Care DHA Dexifol Multi-Vitamin With Fluoride Men's Betaxin CitraNatal Rx NovaMV Multivitamin Super Vitalex Ampoule Buvable Vitafol One Dr. AVi MULTIVITAMIN with Zinc, Real Ginger, Lemon and Lemongrass Hormodausse Plus Calc Et D Tab VitaPhil Aide B Complex With C 550mg Sibergin B - Cap Vitranol Fe Se-Care Conceive Manganese 50mg Plus B1 & E Tab Thiamine HCl Injection - Liq 100mg/ml Cavan Heme OB Folika-V PreferaOB plus DHA Timed Release Vita-vim Srt Vita B + C 500 Tab Vita-amine Cap 100mg CitraNatal Assure Marnatal F Vitamin B Complex Plus 300mg Vitamin C Multitam Liqui Infant Vitamins Vege 1 Daily Tab Maintain Multiple Vitamin & Minerals Great Day/am Formula Tab E.S.T. Complex Prenatal Plus Iron Beminal 500 Tab Poly-Vitamin with Fluoride Children's Chewable Multiple Vitamins (chewable Tablets) Childrens Chewable Vitamins W Iron Children's Chew Multi & Min Tab M.V.I. Pediatric Neonatal DHA Prenatal Plus Vitamins Vasodyn Tab Luna Vitamin and Mineral Bar for Women PureFe Plus Kanga-V Multivitamins & Minerals Cedevita Plus Vitamin Supplement Mvc 9+4 Inj Tendera-OB Ventrixyl Fe Multi Vite Liq Junior OB Complete Prenatal Hemarexin Amp Bewon Elixir Poly-Vite Pediatric Oral Solution Pregvit Ziphex Thiamiject Injection - Liq Im IV 100mg/ml Infant Multivitamin Drops Ultra Hr NESTABS DHA Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA Vitamin B Complex 100 Cedevita Sugar-free Vitamin Supplement B1 Tab 100mg Childrens Chewab Vitamin W Chel Minerals Multiple Vitamins Plus Iron for Women Prenate Star Formula Fm Vitamins & Minerals Tab Vitamin & Mineral Formula 1 Dietary Supplement B Virol Davimet with Fluoride Escavite Lq B1 400mg Ctr Tab PR Natal 400 Mega-vim 75 With Beta-carotene - Tablets DaVITE Onccor PNV Prenatal Vitamin Prenatal Vi-min Tonicol Et A-D-C Ampoules/comprimes Vitrexate FE Poly Vi Flor Chewable Tab Chela-manganese 50 Plus Foltabs Prenatal Plus DHA Ferra Naka Plus Vitamins Daily-Vite NeuroBion Olympian Multi Vit Plus Minerals Tab Milltrium Senior Vitamin and Mineral Supplement Mvc 9 Plus 3 Inj Sopalamine/3b Tab Trinaz Vitafol OB Caplet B-100 Hi Potency B Vitamins Tab Natalvirt Ca Stress Ctr Srt Vitafant Neo-bex Animal Shapes Irospan 24/6 Childrens Chewable Multiple Vitamins W.iron Iberet 500 Only One - Tablet B-100 Caps Tricare Prenatal Compleat Cc II
Indication	For the treatment of thiamine and niacin deficiency states, Korsakov's alcoholic psychosis, Wernicke-Korsakov syndrome, delirium, and peripheral neuritis.
Categories	Alimentary Tract and Metabolism Diet, Food, and Nutrition Food Growth Substances Micronutrients OCT1 substrates OCT2 Inhibitors Physiological Phenomena Pyrimidines Sulfur Compounds Thiazoles Vitamin B Complex Vitamins
ATC-Code	A11DA01
CAS number	70-16-6

Drug Targets

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

Name	Target Sequence	Pharmacological Action	Actions
Thiamine pyrophosphokinase 1	MEHAFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGAN...	unknown	substrate
Pyruvate dehydrogenase E1 component	MSERFPNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLAEARKGGVN...	unknown	cofactor
Cytochrome P450 4B1	MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPP...	unknown	inducer
Thiamine pyrophosphokinase 1	MEHAFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGAN...	unknown	substrate
Nucleoside diphosphate phosphatase ENTPD5	MATSWGTVFFMLVVSCVCSAVSHRNQQTWFEGIFLSSMCPINVSASTLYG...	unknown	substrate
Thiamine-triphosphatase	MAQGLIEVERKFLPGPGTEERLQELGGTLEYRVTFRDTYYDTPELSLMQA...	unknown	substrate
Albumin	MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIA...	unknown	binder
Solute carrier family 22 member 2	MPTTVDDVLEHGGEFHFFQKQMFFLLALLSATFAPIYVGIVFLGFTPDHR...	unknown	inhibitor
Solute carrier family 22 member 1	MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHC...	unknown	substrate
Organic cation/carnitine transporter 2	MRDYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFTGLSSVFLIATPEHRC...	unknown	inhibitor
Thiamine transporter 1	MDVPGPVSRRAAAAAATVLLRTARVRRECWFLPTALLCAYGFFASLRPSE...	unknown	substrate
Thiamine transporter 2	MDCYRTSLSSSWIYPTVILCLFGFFSMMRPSEPFLIPYLSGPDKNLTSAE...	unknown	substrate
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Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682