8UV4 | pdb_00008uv4

M. tuberculosis CTP synthase filament bound to substrates

External Resource: Annotation

Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth R], B [auth V], C [auth X], D [auth b], E [auth A], A [auth R], B [auth V], C [auth X], D [auth b], E [auth A], F [auth E], G, H [auth K], I [auth B], J [auth F], K [auth H], L	CTP synthase	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding CTP synthase activity catalytic activity ligase activity, forming carbon-nitrogen bonds ligase activity cation binding metal ion binding identical protein binding protein binding	pyrimidine-containing compound metabolic process nucleobase biosynthetic process pyrimidine nucleobase biosynthetic process primary metabolic process nucleobase-containing compound metabolic process pyrimidine nucleobase metabolic process biosynthetic process nucleobase-containing small molecule metabolic process nucleobase metabolic process small molecule metabolic process metabolic process cellular process pyrimidine-containing compound biosynthetic process ribose phosphate metabolic process pyrimidine-containing compound metabolic process nucleobase biosynthetic process pyrimidine nucleobase biosynthetic process primary metabolic process nucleobase-containing compound metabolic process pyrimidine nucleobase metabolic process biosynthetic process nucleobase-containing small molecule metabolic process nucleobase metabolic process small molecule metabolic process metabolic process cellular process pyrimidine-containing compound biosynthetic process ribose phosphate metabolic process CTP biosynthetic process nucleotide biosynthetic process carbohydrate derivative metabolic process pyrimidine nucleotide metabolic process ribonucleotide biosynthetic process 'de novo' CTP biosynthetic process pyrimidine ribonucleoside triphosphate biosynthetic process ribonucleotide metabolic process phosphate-containing compound metabolic process pyrimidine nucleoside triphosphate biosynthetic process phosphorus metabolic process ribose phosphate biosynthetic process pyrimidine ribonucleotide metabolic process ribonucleoside triphosphate metabolic process nucleoside phosphate metabolic process carbohydrate derivative biosynthetic process pyrimidine nucleoside triphosphate metabolic process nucleoside triphosphate biosynthetic process nucleobase-containing compound biosynthetic process nucleotide metabolic process CTP metabolic process ribonucleoside triphosphate biosynthetic process organophosphate metabolic process organophosphate biosynthetic process nucleoside phosphate biosynthetic process pyrimidine ribonucleoside triphosphate metabolic process nucleoside triphosphate metabolic process pyrimidine nucleotide biosynthetic process pyrimidine ribonucleotide biosynthetic process	cellular anatomical structure intracellular anatomical structure cytoplasm cytosol

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A [auth R], B [auth V], C [auth X], D [auth b], E [auth A], A [auth R], B [auth V], C [auth X], D [auth b], E [auth A], F [auth E], G, H [auth K], I [auth B], J [auth F], K [auth H], L	IPR029062	Class I glutamine amidotransferase-like	Homologous Superfamily
A [auth R], B [auth V], C [auth X], D [auth b], E [auth A], A [auth R], B [auth V], C [auth X], D [auth b], E [auth A], F [auth E], G, H [auth K], I [auth B], J [auth F], K [auth H], L	IPR004468	CTP synthase	Family
A [auth R], B [auth V], C [auth X], D [auth b], E [auth A], A [auth R], B [auth V], C [auth X], D [auth b], E [auth A], F [auth E], G, H [auth K], I [auth B], J [auth F], K [auth H], L	IPR017456	CTP synthase, N-terminal	Domain
A [auth R], B [auth V], C [auth X], D [auth b], E [auth A], A [auth R], B [auth V], C [auth X], D [auth b], E [auth A], F [auth E], G, H [auth K], I [auth B], J [auth F], K [auth H], L	IPR017926	Glutamine amidotransferase	Domain
A [auth R], B [auth V], C [auth X], D [auth b], E [auth A], A [auth R], B [auth V], C [auth X], D [auth b], E [auth A], F [auth E], G, H [auth K], I [auth B], J [auth F], K [auth H], L	IPR033828	CTP synthase GATase domain	Domain
A [auth R], B [auth V], C [auth X], D [auth b], E [auth A], A [auth R], B [auth V], C [auth X], D [auth b], E [auth A], F [auth E], G, H [auth K], I [auth B], J [auth F], K [auth H], L	IPR027417	P-loop containing nucleoside triphosphate hydrolase	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.