M. tuberculosis CTP synthase filament bound to substrates
Lynch, E.M., Kollman, J.M.To be published.
Experimental Data Snapshot
wwPDB Validation   3D Report Full Report
Entity ID: 1 | |||||
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Molecule | Chains | Sequence Length | Organism | Details | Image |
CTP synthase | 592 | Mycobacterium tuberculosis | Mutation(s): 0  Gene Names: pyrG EC: 6.3.4.2 | ![]() | |
UniProt | |||||
Find proteins for A0A045H225 (Mycobacterium tuberculosis) Explore A0A045H225  Go to UniProtKB:  A0A045H225 | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | A0A045H225 | ||||
Sequence AnnotationsExpand | |||||
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Ligands 3 Unique | |||||
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ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
5ZL (Subject of Investigation/LOI) Query on 5ZL | AA [auth b] CB [auth H] DA [auth A] GB [auth L] HA [auth E] | [[(2~{R},3~{S},4~{R},5~{R})-3,4-bis(oxidanyl)-5-(2-oxidanyl-4-phosphonooxy-pyrimidin-1-yl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate C9 H17 N2 O18 P4 RYGLMDXZXSWNKW-XVFCMESISA-O | |||
ADP (Subject of Investigation/LOI) Query on ADP | BB [auth H] CA [auth A] FB [auth L] GA [auth E] KA [auth G] | ADENOSINE-5'-DIPHOSPHATE C10 H15 N5 O10 P2 XTWYTFMLZFPYCI-KQYNXXCUSA-N | |||
MG Query on MG | AB [auth H] BA [auth b] DB [auth H] EA [auth A] EB [auth L] | MAGNESIUM ION Mg JLVVSXFLKOJNIY-UHFFFAOYSA-N |
Task | Software Package | Version |
---|---|---|
MODEL REFINEMENT | ISOLDE | |
MODEL REFINEMENT | PHENIX |
Funding Organization | Location | Grant Number |
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National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS) | United States | R35 GM149542 |